PLOS Global Public Health recently hosted a roundtable with the lead authors of ISN-Global Kidney Health Atlas (ISN-GKHA) articles they published earlier this year. The authors highlight key insights from their research, which examined disparities in the availability, affordability, quality, and access to kidney care services across countries categorized by World Bank income group classifications. Watch...
The ISN-ACT Toolkit now features a section on Standard Operating Procedures (SOPs) in clinical trials to help improve clarity, consistency, and traceability in clinical trial processes. Access the SOP section of the ISN Clinical Trials Toolkit here Contributed by ISN-Advancing Clinical Trials Committee member Paula Andrea Marioli (Argentina) and colleagues, the section includes: Suggested SOP format – a structured guide...
PLOS Global Public Health recently published a series of articles using data from the third edition of the ISN-Global Kidney Health Atlas (ISN-GKHA), exploring gaps in availability, affordability, quality, and access to kidney care services across countries by World Bank income group classifications. Read the individual papers in PLOS Global Public Health: “Landscape of kidney replacement...
PLOS Global Public Health recently published a series of articles using data from the third edition of the ISN-Global Kidney Health Atlas (ISN-GKHA), exploring gaps in availability, affordability, quality, and access to kidney care services across countries by World Bank income group classifications. Read the individual papers in PLOS Global Public Health: “Landscape of Kidney Replacement...
Kidney International® KDIGO 2025 Clinical Practice Guideline for the Evaluation, Management, and Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD): Executive Summary The KDIGO 2025 Clinical Practice Guideline for ADPKD is the first global guideline on the evaluation, management, and treatment of this genetic disorder, focusing on areas such as diagnosis, kidney manifestations, disease progression, and extrarenal...
The ISN-KI/KIR Editorial Fellows Session: The Best of 2024/25 Articles will take place at WCN’25 on Saturday, February 8, 2025, from 9:45-11:15 a.m. KI-ISN Early-Career Researcher Awardees and ISN-KI Editorial Fellows will be honored during this session. KI-ISN Early-Career Researcher Awards honor exceptional basic and clinical science research published in Kidney International® (KI) in the...
The accepted abstracts for the ISN World Congress of Nephrology (WCN) 2025 are now published in the latest supplement to Kidney International Reports®. Read the abstracts here WCN’25 registration is possible on-site from February 5 – find out more here.
In December 2024, the ISN conducted a Scientific Writing Course (SWC) in Taiwan, co-hosted and co-supported by the Taiwan Society of Nephrology (TSN). The course equipped participants with the tools and confidence to craft high-quality research publications. Delegates follow the ISN SWC course with tailored guidance from course faculty Testimonials from participants highlight the course's value: "The...
Kidney International® A Sub-study of the POISE-3 Randomized Trial Examined Effects of a Perioperative Hypotension-avoidance Strategy Versus a Hypertension-avoidance Strategy on the Risk of Acute Kidney Injury This sub-study of the POISE-3 trial investigated whether a strategy to prevent low blood pressure during surgery could reduce the risk of acute kidney injury (AKI). Researchers randomized 7,307 patients...
As we step into 2025, we reflect on the impactful ISN-led research of 2024. These studies deepen our understanding of kidney health and advance global kidney care as a health priority. Below, we highlight some of the year’s key contributions: An Update on the Global Disparities in Kidney Disease Burden and Care Across World Countries...
Watch the video here This video abstract was supported by Vera Therapeutics
The High-impact Trials (HIT) sessions at WCN'25 promise exciting insights and findings from cutting-edge research in kidney care and related fields, including: The FLOW Trial investigating semaglutide's impact on kidney outcomes and cardiovascular safety The REGENCY Trial on improving renal response rates in lupus nephritis with Obinutuzumab The ZEUS Trial evaluating ziltivekimab's potential for cardiovascular protection in...
This visual abstract was supported by Vera Therapeutics. Download Visual Abstract
The ISN congratulates its newest ISN-Named Fellows: Megan Borkum and Neeru Agarwal for ISN-ACT (clinical trials) Rajitha A. Abeysekera for SharE-RR (registries) Somkanya Tungsanga, Nivedita Kamath, Victoria Nkunu, Caner Alparslan, Viviane Calice-Silva, Abduzhappar Gaipov, Anna Francis and Maria Pippias, for ISN-GKHA (ISN-Global Kidney Health Atlas) Learn more about our ISN-Named Fellows here These early-career ISN members were approved as ISN-Named...
Two significant research studies were accepted as late-breaking clinical trials at Kidney Week 2024 and have subsequently been published in Kidney International®. Higher Intraoperative Blood Pressure Does Not Reduce Acute Kidney Injury in Non-Cardiac Surgery: What Do the Results of the POISE-3 Trial Tell Us? The POISE-3 trial's analysis found no benefit in targeting a...
The ISN PARADIGM meeting took place in Vancouver, BC, Canada, from November 22-23, 2024. The meeting gathered clinicians, trialists, patient partners, regulators, and industry scientists to rethink current concepts of laboratory values in chronic kidney disease (CKD) populations, the value of patient-reported outcomes, and trial designs while fostering a robust culture of clinical trials. The program...
Kidney International® Patients With Crush Syndrome and Kidney Disease: Lessons Learned From the Earthquake in Kahramanmaraş, Türkiye This study assessed in-hospital outcomes and related factors in 1,024 adult patients diagnosed with post-earthquake crush syndrome following the 2023 earthquakes in Kahramanmaraş, Türkiye. A 9.8% mortality rate was reported. Nonsurvivors were older, were more likely to have preexisting chronic...
Nephrology has published the paper "Structures for Quality Assurance and Measurements for Kidney Replacement Therapies: A Multinational Study From the ISN-GKHA" by Ekrikpo et al. This study evaluates the capacity for delivering quality kidney failure care globally using data from the 2023 ISN Global Kidney Health Atlas (GKHA). The findings highlight variability in quality assurance standards,...
Kidney International® NAVKIDS2: A Lesson in Matching Outcomes Measures to Interventions The Randomized Controlled Trial (NAVKIDS2) of a Patient Navigator Program Created for Children With Chronic Kidney Disease These two studies evaluate a patient navigation program for children from disadvantaged backgrounds with chronic kidney disease (CKD), aiming to improve access to evidence-based care. While the patient navigation...
Effect of Alcohol-Mediated Renal Denervation on Blood Pressure in the Presence of Antihypertensive Medications: Primary Results From the TARGET BP I Randomized Clinical Trial Kandzari et al, Circulation, 2024 Jun 11;149(24):1875-1884 ISN-ACT Global Trials Focus coordinator Megan Borkum summarizes the design and outcomes of one of the latest ISN-ACT Global Trials Focus (GTF) selections. Summary: The TARGET...
