Tag - research

Optimize trial integrity: New SOP and ethics resources in the ISN-ACT Clinical Trials Toolkit 

The ISN-ACT Toolkit now features a section on Standard Operating Procedures (SOPs) in clinical trials to help improve clarity, consistency, and traceability in clinical trial processes.   Access the SOP section of the ISN Clinical Trials Toolkit here  Contributed by ISN-Advancing Clinical Trials Committee member Paula Andrea Marioli (Argentina) and colleagues, the section includes:  Suggested SOP format – a structured guide...

March 24, 2025News, ResearchRead more...

PLOS articles spotlight ISN-GKHA 2023 findings on the international state of kidney care

PLOS Global Public Health recently published a series of articles using data from the third edition of the ISN-Global Kidney Health Atlas (ISN-GKHA), exploring gaps in availability, affordability, quality, and access to kidney care services across countries by World Bank income group classifications.  Read the individual papers in PLOS Global Public Health:   “Landscape of kidney replacement...

February 24, 2025News, ResearchRead more...

ISN’s Global Kidney Health Atlas 2023 Data Addresses Kidney Care Gaps in Resource-limited Settings

PLOS Global Public Health recently published a series of articles using data from the third edition of the ISN-Global Kidney Health Atlas (ISN-GKHA), exploring gaps in availability, affordability, quality, and access to kidney care services across countries by World Bank income group classifications. Read the individual papers in PLOS Global Public Health: “Landscape of Kidney Replacement...

February 12, 2025News, ResearchRead more...

ISN Journal Summaries on Clinical Practice Guideline for ADPKD and Mitochondrial Function in Diabetic Kidney Disease

Kidney International® KDIGO 2025 Clinical Practice Guideline for the Evaluation, Management, and Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD): Executive Summary The KDIGO 2025 Clinical Practice Guideline for ADPKD is the first global guideline on the evaluation, management, and treatment of this genetic disorder, focusing on areas such as diagnosis, kidney manifestations, disease progression, and extrarenal...

February 3, 2025Journals, NewsRead more...

Meet the KI-ISN Early-Career Researchers and ISN-KI Editorial Fellows!

The ISN-KI/KIR Editorial Fellows Session: The Best of 2024/25 Articles will take place at WCN’25 on Saturday, February 8, 2025, from 9:45-11:15 a.m.  KI-ISN Early-Career Researcher Awardees and ISN-KI Editorial Fellows will be honored during this session. KI-ISN Early-Career Researcher Awards honor exceptional basic and clinical science research published in Kidney International® (KI) in the...

February 3, 2025Awards, Journals, NewsRead more...

Strengthening Global Nephrology: Highlights From Taiwan 

In December 2024, the ISN conducted a Scientific Writing Course (SWC) in Taiwan, co-hosted and co-supported by the Taiwan Society of Nephrology (TSN). The course equipped participants with the tools and confidence to craft high-quality research publications. Delegates follow the ISN SWC course with tailored guidance from course faculty Testimonials from participants highlight the course's value: "The...

January 21, 2025Grants, News, Scientific Writing CourseRead more...

ISN Journal Summaries on Hypertension-avoidance Strategies and Age-based GFR    

Kidney International®  A Sub-study of the POISE-3 Randomized Trial Examined Effects of a Perioperative Hypotension-avoidance Strategy Versus a Hypertension-avoidance Strategy on the Risk of Acute Kidney Injury  This sub-study of the POISE-3 trial investigated whether a strategy to prevent low blood pressure during surgery could reduce the risk of acute kidney injury (AKI).   Researchers randomized 7,307 patients...

January 6, 2025Journals, News, ResearchRead more...

Celebrating ISN’s 2024 Publications: Driving Kidney Research for Better Patient Outcomes 

As we step into 2025, we reflect on the impactful ISN-led research of 2024. These studies deepen our understanding of kidney health and advance global kidney care as a health priority. Below, we highlight some of the year’s key contributions:    An Update on the Global Disparities in Kidney Disease Burden and Care Across World Countries...

January 6, 2025Journals, News, ResearchRead more...

Exploring Groundbreaking Research: Introducing High-impact Trials at WCN’25

The High-impact Trials (HIT) sessions at WCN'25 promise exciting insights and findings from cutting-edge research in kidney care and related fields, including: The FLOW Trial investigating semaglutide's impact on kidney outcomes and cardiovascular safety The REGENCY Trial on improving renal response rates in lupus nephritis with Obinutuzumab The ZEUS Trial evaluating ziltivekimab's potential for cardiovascular protection in...

December 9, 2024News, Research, WCNRead more...

Celebrating Excellence: Meet Eleven New ISN-Named Fellows

The ISN congratulates its newest ISN-Named Fellows: Megan Borkum and Neeru Agarwal for ISN-ACT (clinical trials) Rajitha A. Abeysekera for SharE-RR (registries) Somkanya Tungsanga, Nivedita Kamath, Victoria Nkunu, Caner Alparslan, Viviane Calice-Silva, Abduzhappar Gaipov, Anna Francis and Maria Pippias, for ISN-GKHA (ISN-Global Kidney Health Atlas) Learn more about our ISN-Named Fellows here These early-career ISN members were approved as ISN-Named...

December 9, 2024Education, News, ResearchRead more...

New Perspectives on Treatment Protocols: Kidney International® Publishes Late-breaking Clinical Trials

Two significant research studies were accepted as late-breaking clinical trials at Kidney Week 2024 and have subsequently been published in Kidney International®. Higher Intraoperative Blood Pressure Does Not Reduce Acute Kidney Injury in Non-Cardiac Surgery: What Do the Results of the POISE-3 Trial Tell Us?   The POISE-3 trial's analysis found no benefit in targeting a...

November 26, 2024Journals, News, ResearchRead more...

The ISN Holds Consensus Meeting on Changing Paradigms of Studies in CKD

The ISN PARADIGM meeting took place in Vancouver, BC, Canada, from November 22-23, 2024. The meeting gathered clinicians, trialists, patient partners, regulators, and industry scientists to rethink current concepts of laboratory values in chronic kidney disease (CKD) populations, the value of patient-reported outcomes, and trial designs while fostering a robust culture of clinical trials. The program...

November 26, 2024Initiatives, News, ResearchRead more...

Latest ISN Journal Editorial Selections

Kidney International® Patients With Crush Syndrome and Kidney Disease: Lessons Learned From the Earthquake in Kahramanmaraş, Türkiye This study assessed in-hospital outcomes and related factors in 1,024 adult patients diagnosed with post-earthquake crush syndrome following the 2023 earthquakes in Kahramanmaraş, Türkiye. A 9.8% mortality rate was reported. Nonsurvivors were older, were more likely to have preexisting chronic...

November 12, 2024Journals, NewsRead more...

2023 ISN-GKHA Paper on Quality and Monitoring of Kidney Care Published in Nephrology

Nephrology has published the paper "Structures for Quality Assurance and Measurements for Kidney Replacement Therapies: A Multinational Study From the ISN-GKHA" by Ekrikpo et al. This study evaluates the capacity for delivering quality kidney failure care globally using data from the 2023 ISN Global Kidney Health Atlas (GKHA). The findings highlight variability in quality assurance standards,...

October 28, 2024News, ResearchRead more...

Latest ISN Journal Editorial Selections

Kidney International®  NAVKIDS2: A Lesson in Matching Outcomes Measures to Interventions   The Randomized Controlled Trial (NAVKIDS2) of a Patient Navigator Program Created for Children With Chronic Kidney Disease   These two studies evaluate a patient navigation program for children from disadvantaged backgrounds with chronic kidney disease (CKD), aiming to improve access to evidence-based care.   While the patient navigation...

October 14, 2024Journals, News, ResearchRead more...

A New Intervention for TARGETing Resistant Hypertension

Effect of Alcohol-Mediated Renal Denervation on Blood Pressure in the Presence of Antihypertensive Medications: Primary Results From the TARGET BP I Randomized Clinical Trial Kandzari et al, Circulation, 2024 Jun 11;149(24):1875-1884 ISN-ACT Global Trials Focus coordinator Megan Borkum summarizes the design and outcomes of one of the latest ISN-ACT Global Trials Focus (GTF) selections. Summary: The TARGET...

October 14, 2024News, ResearchRead more...

Save the Date: ISN-ANIO Workshop on Global Clinical Trials in Diverse Populations – Registration Opening Soon!

The clinical trials workshop will be held on February 5, 2025, at the Pride Plaza Aerocity in New Delhi, India, directly preceding the ISN World Congress of Nephrology 2025 (WCN’25) from February 6-9, 2025. It is organized by the ISN-ANIO committee, a collaboration between the ISN and the American Nephrologists of Indian Origin (ANIO) This...

October 14, 2024News, WCNRead more...