Tag - podocyte injury

Latest ISN Journal Editorial Selections

Kidney International®  Repurposing Drugs for Diseases Associated With Podocyte Dysfunction Podocyte disorders often lead to chronic kidney disease and kidney failure, with current treatments relying on nonspecific immunosuppressants that have serious side effects.   Recent advances in understanding the molecular mechanisms of podocyte injury offer new opportunities, including the potential to repurpose existing FDA-approved drugs for kidney-related uses.   This...

Read the Latest ISN Journal Editorial Selections

Kidney International® Repurposing Drugs for Diseases Associated With Podocyte Dysfunction Due to recent advances in understanding the molecular and cellular mechanisms underlying podocyte injury, there is potential for repurposing already approved therapeutics for treating these disorders. This mini-review explores the complexities of repurposing drugs for kidney treatment, emphasizing the importance of extensive testing, emerging technologies, early intervention,...