An updated edition of the ISN-ACT Clinical Trials Toolkit is now available. It includes additional content and new resources. The Toolkit was updated and improved based on feedback from the ISN-ACT Toolkit subgroup and the nephrology community. The Toolkit is an ISN open-access, online resource to guide trial design, study conduct, data management, data analysis, and publications....
The ISN Webinar, Dissemination and Implementation of Therapies for Kidney Diseases in Low- and High-Income Countries, will be broadcast on Thursday, April 29, at 3 p.m. CEST (convert to your time zone here). Register here. SGLT2i inhibitors protect the heart and the kidney, but equitable access to these and other drugs for Chronic Kidney Disease and...
The objective of the ISN Global Kidney Health Atlas (GKHA) is to provide a snapshot of individual country and regional health system characteristics, as well as specific elements relevant to the management of patients with kidney failure in terms of the WHO health systems building blocks. Our collection of manuscripts from the ten ISN regions,...
The ISN i3C (International Consortium CKDu Collaborators) group has redesigned the ISN Observatory of CKDu map. Access the map and share your data here. The map facilitates collaboration and data exchange to raise awareness of the urgent issue of chronic kidney disease of unknown etiology (CKDu). This initiative was developed as part of ISN’s 2018-2020 Collaboration Plan...
The ISN and KDIGO have partnered to create tools on CKD early identification and intervention for kidney health professionals, primary care physicians, and nurses working in primary care settings. Access the toolkit here. The ISN-KDIGO CKD Early Identification & Intervention Toolkit includes quick guides, infographics, teaching tools, as well as research articles, webcasts, and reports. The toolkit...
To illustrate the ISN-ACT Clinical Trials Toolkit’s usability and facilitate understanding of important clinical trial methodologies, ISN-ACT Clinical Trials Toolkit subgroup members are developing a series of stories based on various toolkit topics. The first of these narratives, by Augusto Cesar Soares dos Santos and Brendan Smyth, outlines trial randomization methods through a fictional clinical...
The ISN-KI Early-career Researcher Award recognizes outstanding research in basic and clinical science published in Kidney International (KI) in 2019 and 2020. The winners are: Basic science Sho Hasegawa (Japan) Comprehensive three-dimensional analysis (CUBIC-kidney) visualizes abnormal renal sympathetic nerves after ischemia/reperfusion injury Qi Cao (Australia) Regulatory innate lymphoid cells suppress innate immunity and reduce renal ischemia/reperfusion injury Clinical science Madhav C. Menon (USA) Genome-wide...
Kidney International has published the KDIGO Clinical Practice Guideline for management of blood pressure (BP) in chronic kidney disease (CKD), which replaces the 2004 Kidney Disease Quality Outcomes Initiative document on the same topic. This new guideline is designed to help physicians in their clinical decision-making for patients with CKD who are not receiving dialysis. The...
Agnes Fogo, ISN President-elect, is a co-author on AI Applications in Renal Pathology published in Kidney International. The paper presents an integrated review on current and future applications in AI-assisted renal pathology, including data collection and analysis in full-stack AI-assisted renal pathology studies and renal pathology-optimized AI techniques. Since synergetic developments of renal pathology and AI...
The #NephTrials initiative is an exciting new series of conversations combining: The ISN-ACT Global Trials Focus, identifying and summarizing recent interesting trials relevant to kidney disease. The ISN-ACT Toolkit, guiding anyone wishing to start a clinical trial. Social media expertise from the #NephJC community through blog posts, visual abstracts, and a discussion on each topic held on...
The ISN-KI Early-career Researcher Award recognizes outstanding research in basic and clinical science published in Kidney International (KI) in 2019 and 2020. Papers will be assessed on the novelty of research, robustness, and methodologies. Nominate your candidate here before February 23. Only ISN members are eligible to nominate candidates who are: Primary authors ISN members Early-career researchers (less than...
Help expand trial participation within the nephrology community: Join colleagues online for a lively exchange of ideas on February 16 at 9 p.m. ET. #NephTrials The ISN-ACT (Advancing Clinical Trials) and NephJC are partnering on the #NephTrials initiative to increase awareness of ongoing trials in nephrology and improve understanding of what it takes to design and conduct clinical trials. The #NephTrials initiative is an exciting new series...
Every month the ISN-ACT Team lists interesting new randomized controlled trials (RCTs) from around the world. Highlights: Daily, weekly, or monthly cholecalciferol dosing regimens are similarly effective in children with CKD View the latest trials here. A summary of the highlighted trial is now available in French, Mandarin, Russian, and Spanish. Support equal access to nephrology research: Become an ISN...
The ISN-ACT (Advancing Clinical Trials) and NephJC are partnering to increase awareness of ongoing trials in nephrology and improve understanding of what it takes to design and conduct clinical trials, especially in terms of different trial designs. The ISN-ACT produces the Global Trials Focus, a monthly list that identifies and summarizes recent interesting trials relevant...
The ISN-Advancing Clinical Trials (ISN-ACT) initiative developed the paper, “The International Society of Nephrology Advancing Clinical Trials (ISN-ACT) Network: current activities and future goals,” which is now available in the December edition of Kidney International (KI). The manuscript highlights the need for high-quality clinical trials in the field of nephrology. It outlines the ISN-ACT network’s...
The paper, “Availability and Affordability of Kidney Health Laboratory Tests around the Globe,” has been published in the American Journal of Nephrology. The manuscript, produced by the KDIGO Controversies Conference leaders in collaboration with ISN, surveyed a representative subset of ISN-Global Kidney Health Atlas (ISN-GKHA) respondents from April to June 2020 to ascertain the availability and...
The ISN had an exciting start to research projects in 2020 with the Research Collaborative Meeting and 1ST International Consensus Meeting on Defining Kidney Failure in Clinical Trials that took place from January 31 - February 1 in Vancouver, Canada. The ISN convened this international, multi-stakeholder meeting to develop consensus on definitions of kidney failure...
The ISN Executive Committee and Council have approved four “ISN-Named Fellows.” These ISN members – early-career nephrologists – have contributed significantly to various outputs of ISN’s research activities. Find out more about these ISN-Named Fellows here. ISN GKHA Fellow – Isabelle Ethier Dr. Isabelle Ethier from Centre Hospitalier de l’Université de Montréal (Canada) has been awarded the title...
The American Journal of Nephrology (AJN) has published the ISN-KDIGO manuscript, “Availability and Affordability of Kidney Health Laboratory Tests Around the Globe.” Read the full, open-access article here. Laboratory testing of kidney health measures is essential to diagnose and monitor kidney diseases. The availability and affordability of kidney health laboratory tests across countries remain largely undefined. The...
Every month the ISN-ACT Team lists interesting new randomized controlled trials (RCTs) from around the world. Highlight: Corticosteroids and cyclophosphamide may be superior to tacrolimus and rituximab in the treatment of primary membranous nephropathy at the cost of increased adverse events See the latest trials here. A summary of the highlighted trial is now available in French, Mandarin,...
