Research

Latest ISN Journal Summaries

Kidney International ® Editorial Selections The Power of “Negative” Experiments: Harry Goldblatt’s Pathway to Discovering How Renal Ischemia Causes Hypertension The author demonstrates that Harry Goldblatt’s willingness to conduct and publish studies with negative outcomes led to a fundamental understanding of blood pressure control within less than a decade of his initial discovery, published in...

Listen to the Discussion on ISN’s First Consensus Guidance for Pre-clinical Animal Studies in Translational Nephrology (TRANSFORM) with Fergus Caskey, Masaomi Nangaku and Agnes Fogo

Fergus Caskey, chair of the ISN Research Working Group, interviews ISN President Masaomi Nangaku and immediate Past President Agnes Fogo on the first guidance for the optimal conduct of translational animal studies for developing new drugs to treat kidney disease. Listen to the ISN Global Kidney Care Podcast here. Learn about: The initiative’s goal of improving translational...

Newly Revised Edition of the ISN-ACT Clinical Trials Toolkit Available Now!

The ISN-ACT Clinical Trials Toolkit, launched in 2020, is designed to guide anyone starting a clinical trial or participating as a trial site. This user-friendly online toolkit is for nephrologists and researchers in kidney care from all parts of the world – regardless of their level of clinical trial experience or local resources. The toolkit includes...

“Trying to Solve the Mystery of CKDu Together”: The ISN i3C “Work in Progress” Meetings Highlight Advances and Research Opportunities in CKDu

ISN i3C Network members and ISN staff at one of the recently held "Work in Progress" meetings The ISN i3C (CKDu) Network (International Consortium CKDu Collaborators) brought together more than 80 participants at two online interactive meetings held in June and July to discuss current, notable work on chronic kidney disease of unknown origin (CKDu). In...

Kidney International® Publishes ISN First Consensus Guidance for Pre-clinical Animal Studies in Translational Nephrology 

Kidney International® has published the "International Society of Nephrology First Consensus Guidance for Pre-clinical Animal Studies in Translational Nephrology." This open-access paper was developed from the "First Consensus Meeting on Guidance for Optimal Pre-Clinical Animal Studies in Translational Nephrology" (TRANSFORM) hosted by the ISN in Brussels, Belgium, in October 2022. This is the first such guidance. The recommendations...

“It’s an Extraordinary Global Effort”: Liz Lightstone Introduces the 2023 ISN-Global Kidney Health Atlas; Speakers David Johnson and Ikechi Okpechi  Comment on Findings – Watch the Webinar Recording Now!

Watch a recording of the ISN Webinar "ISN-GKHA (Atlas): Findings and Policy Implications for Europe and for the Americas" here. Moderator Liz Lightstone joined speakers David Johnson and Ikechi Okpechi to discuss the extent of gaps in provision and access to kidney care across Europe and the Americas. The recently published 2023 ISN-Global Kidney Health Atlas...

Discuss the SWIFT Trial Live With ISN and Key Experts During the Upcoming #NephTrials on July 18

Join Rachael Morton, principal investigator of the SWIFT trial, in conversation with ISN-ACT (clinical trials) Committee members Michael Walsh and Angela Yee Moon Wang* at 9 p.m. EDT (convert to your time zone here) on July 18.  They will be joined by #NephJC representatives Swapnil Hiremath and Joel Topf to discuss the protocol for...

Catch Up Now! Watch a Recording of the ISN Webinar on the First Consensus Guidance for Pre-clinical Animal Studies in Translational Nephrology (TRANSFORM)

The ISN webinar on the first guidance on the optimal conduct of translational animal studies for developing new drugs to treat kidney disease took place on May 30, 2023. Watch the recording here. Moderators Agnes Fogo and Fergus Caskey* discussed the guidance with ISN President Masaomi Nangaku and TRANSFORM meeting Steering Committee member Richard Kitching. The guidance...

 “Get Involved – It’s Incredibly Rewarding!”: Meg Jardine Discusses Clinical Trials Alongside Adeera Levine in the Latest ISN Global Kidney Care Podcast

Listen to the podcast here. Michele Provenzano and Daniel O'Hara, coordinators of the ISN-ACT Global Trials Focus (GTF)*, interview international clinical trial experts and ISN-ACT (Advancing Clinical Trials) chair and deputy chair Meg Jardine and Adeera Levin. Get involved in international clinical trials in nephrology: Join the ISN-ACT Network here. Meg Jardine talks about some of...

“A Truly Fantastic Resource”: Watch the Interview With ISN-GKHA Leads on the Third Edition of the ISN-Global Kidney Health Atlas

The third edition of the ISN-Global Kidney Health Atlas (ISN-GKHA) was launched at the World Congress of Nephrology 2023. Watch the video here. Adeera Levin, ISN-GKHA founder and lead, and ISN-GKHA Co-chairs David Johnson and Aminu Bello presented features and findings from the latest edition during an interview recorded at the ISN Kidney Studio. Download the 2023...

ISN Members – Watch More Free Content From the WCN’23 Spotlight Sessions!

Roberto Pecoits-Filho and Amina Rakisheva discuss the Optimization of RAASi Therapy Toolkit on the Spotlight Stage at WCN'23 Watch the WCN'23 Spotlight Sessions here. A Nephrology-Cardiology Initiative: Optimization of RAASi Therapy Toolkit* Roberto Pecoits-Filho, ISN Research Working Group member, and Amina Rakisheva, representing the Heart Failure Association of the European Society of Cardiology (HFA-ESC), discuss the...

Discover the Latest Video Abstracts

Watch the latest ISN video abstracts from the @ISNeducation Social Media Team. Watch the videos here. The videos are based on papers from Kidney International® and Kidney International Reports®: A Novel Direct Adenosine Monophosphate Kinase Activator Ameliorates Disease Progression in Preclinical Models of Autosomal Dominant Polycystic Kidney Disease Transitional B cell Cytokines Risk Stratify Early Borderline Rejection After Renal...

Listen to the ISN Global Kidney Care Podcast on the EMPA-KIDNEY Trial Data with ISN President Masaomi Nangaku, Adeera Levin and Will Herrington

Listen to the podcast here. Tune in to hear from host Adeera Levin, head of the Nephrology Division, University of British Columbia, who is joined by: Will Herrington, honorary consultant nephrologist, Oxford Kidney Unit ISN President Masaomi Nangaku, head of the Nephrology and Endocrinology Division, University of Tokyo Graduate School of Medicine This episode presents the latest updates following a webinar...

Explore the Newly Revised Edition of the ISN-ACT Clinical Trials Toolkit

Access the third edition of the ISN-ACT Clinical Trials Toolkit here. The toolkit, launched in 2020, was designed to guide anyone wishing to start a clinical trial or participate as a trial site. Watch a short introductory video on the toolkit here. Listen to a podcast here. This user-friendly online toolkit is for nephrologists and researchers in...

ISN iNET-CKD Experts, Maarten Taal and Adeera Levin, Discuss a Recent Collaborative Study on Anemia in CKD Patients – Watch the Interview!

Maarten Taal, ISN iNET-CKD* chair, and Adeera Levin, co-principal investigator of the ISN iNET-CKD anemia study, discuss the ISN iNET-CKD collaborative project "Exploring International Variability in Hemoglobin and the Approach to Anemia Treatment Among Individuals With CKD" in an interview recorded at the ISN Kidney Studio at WCN'23. Maarten Taal and Adeera Levin discuss the...

Kidney International Publishes ISN Paper on Implementing Early CKD Detection Programs

As the global burden of chronic kidney disease (CKD) rises, “Perspectives on Early Detection of CKD: The Facts, the Questions, and a Proposed Framework for 2023 and Beyond” presents timely information from ISN leaders on early CKD detection and a framework for adoption. Read the paper in Kidney International here. This paper culminates two years of work that...

Kidney International Publishes ISN First Consensus Guidance for Pre-Clinical Animal Studies in Translational Nephrology

Kidney International has published the "International Society of Nephrology First Consensus Guidance for Pre-clinical Animal Studies in Translational Nephrology." The paper was developed from the First Consensus Meeting on Guidance for Optimal Pre-Clinical Animal Studies in Translational Nephrology (TRANSFORM) hosted by the ISN in Brussels, Belgium, in October 2022. Pre-clinical tests in animal models are key steps in...