Defining Measures of Kidney Function In Observational Studies Using Routine Health Care Data: Methodological and Reporting Considerations This review illustrates the diversity of working definitions of kidney disease in scientific literature and discusses the advantages and limitations of the most commonly used approaches. The authors summarize ways to identify and overcome possible biases and propose a framework...
The ISN Clinical Research Program (CRP) offers grants to researchers in low, lower-middle, and upper-middle-income countries to support research projects on detecting and managing noncommunicable chronic diseases such as CKD, AKI, hypertension, diabetes, and cardiovascular disease. Apply to the program here. Regional coordinators must receive the application by April 1. Final applications are accepted once per...
Did you miss the live session? A recording is available here. Professor Meg Jardine, ISN-ACT (Advancing Clinical Trials) Committee chair, and speakers David Wheeler, Jonathan Barratt and Jodie Babitt joined in a lively discussion on this treatment option and on the management of anemia in CKD patients. This webinar is supported by Astellas.
Clockwise, from top left: Carinna Hockham, Anastasiia Zykova, Suman Behera and Mark Canney The ISN Executive Committee and Council have approved four “ISN-Named Fellows.” Please join us in congratulating Suman Behera from ISN I3C (CKDu), Mark Canney from ISN iNET-CKD (cohort studies), and Anastasiia Zykova and Carinna Hockham from ISN-ACT (clinical trials). Get to know our new ISN-Named Fellows here. These early-career ISN...
Kidney International Particulate Matter of Air Pollution May Increase Risk of Kidney Failure in IgA Nephropathy. Environmental pollution has been associated with the progression of chronic kidney disease in the general population. This study specifically investigated the influence of exposure to fine particulate matter less than 2.5 μm in diameter (PM2.5) on IgAN progression. Kidney International Reports Leveraging...
The sixth narrative-based chapter of the Clinical Trials (ISN-ACT) Toolkit describes best practices when writing a scientific paper to boost the impact of your published study. Discover chapter 6 here alongside previous chapters. This series of narratives is produced by the ISN-ACT Clinical Trials Toolkit subgroup members based on topics from the ISN-ACT Clinical Trials Toolkit,...
Watch the latest ISN video abstracts from the @ISNeducation Social Media Team on inhibiting inflammation with anti-cytokine therapy and post-dilution hemodiafiltration. Watch the videos here The videos are based on papers from Kidney International and Kidney International Reports: A Randomized Controlled Pilot Trial of Anakinra for Hemodialysis Inflammation High-volume Hemodiafiltration and Cool Hemodialysis Have a Beneficial Effect on Intradialytic...
The first ISN Global Trials Focus (GTF) Twitter Space took place on November 17, 2022. The interactive live audio discussion focused on the GTF project and the TESTING (Therapeutic Evaluation of Steroids in IgA Nephropathy Global) randomized clinical trial on oral methylprednisolone. Access the Twitter Space conversation here. The event generated much interest, with...
Join the ISN Global Trials Focus (GTF) editorial team and researchers from the TESTING* study for a live audio discussion on the GTF project and the TESTING randomized clinical trial on oral methylprednisolone. Access the Twitter Space conversation here on November 17, 2022, at 10 p.m. CET. Scan the QR code in the image above to...
The paper "Kidney Function in Factory Workers Exposed to Heat Stress - a 2-year Follow-up Study" by Fabiana Nerbass has been published in the Journal of Occupational of Environmental Medicine. Read the article here. The research highlights the value of collaboration among investigators, organizations and communities. Fabiana Nerbass, from Fundação Pró-Rim in Joinville, Brazil, received the...
The first ISN Global Trials Focus (GTF) Twitter Space will be held on November 17, 2022, at 10 p.m. CET. The live audio discussion will address the GTF initiative and the Therapeutic Evaluation of Steroids in IgA Nephropathy Global (TESTING) Randomized Clinical Trial, “Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in...
The ISN’s TRANSFORM meeting (TRAnslational Nephrology Science FOR new Medications) took place in Brussels, Belgium, from October 8-9, 2022. The meeting gathered patients, clinical and academic researchers, regulators, and industry partners to: Report ISN Research Working Group activities describing the current landscape and future possibilities. Reach consensus on guidance that optimizes animal study design and drives the...
The paper “Community Engagement in Kidney Research: Guatemalan Experience" by Angie Aguilar-González was recently published in BMC Nephrology. Read the article here. The research highlights the value of collaborative research between investigators, organizations and communities. Angie Aguilar-González, from FUNDANIER (Fundación para el Niño Enfermo Renal) in Guatemala City, Guatemala, received the 2018 'Hydration and Kidney Health...
Naoka Murakami, 2022 ISN-KI Early-Career Research Award winner, will present at two upcoming oncology-nephrology meetings. The Onco-Nephrology Symposium, 2022, will take place in hybrid format on September 30 in Boston, USA. The event offers up-to-date information and insights from national and international experts in this constantly evolving subspecialty. Join Naoka Murakami for 'Immune Checkpoint Inhibitors and...
Connect with Fergus Caskey, Roberto Pecoits-Filho, Michael Walsh, Joel Topf, Manasi Bapat, and Swapnil Hiremath at the latest #NephTrials discussion on September 29, 2022, at 1 p.m. CEST. Why do we need more efficient clinical trials? What is a registry and why are registries useful? What is a registry-based randomized controlled trial, and how does...
Are you planning a research project but need help with statistics? Access the new chapter here. This narrative-based chapter of the Clinical Trials (ISN-ACT) Toolkit guides you through key statistical concepts to help you identify variables and use a design study best suited to the data type and target population. The fictional narrative addresses: Descriptive and inferential statistics Primary...
The upcoming narrative-based chapter of the Clinical Trials (ISN-ACT) Toolkit will describe descriptive and inferential statistics to help you easily get to grips with building a statistical analytical plan. The new chapter will be released in July 2022. This series of narratives is produced by ISN-ACT Clinical Trials Toolkit subgroup members based on topics from the ISN-ACT...
Held in May, the meeting brought together 40 members of the ISN i3C (International Consortium CKDu Collaborators) network and the ISN Renal Pathology Working Group The meeting highlighted the need to increase kidney biopsies in CKDu (chronic kidney disease of unknown origin) and improve biopsy preservation. Three ISN i3C network members presented: Richard Johnson outlined the usefulness of kidney...
Would you like to understand the key design elements of a cohort study and learn how to draft a study protocol? Watch the first iNET-CKD webinar, "Building a Cohort Study: Insight from Investigators," here. More than 200 people attended the webinar on May 10, generating a lively conversation on Twitter: Access the thread here. Participants came...
The ISN Observatory of CKDu is a catalog where researchers can submit their findings or view other studies. This system facilitates global collaboration and data exchange, enabling researchers to know what studies are ongoing at any given time. The initiative was developed by the ISN i3C (International Consortium CKDu Collaborators) working group as part of...
