Research

Use of Self-educational Materials Can Help Decrease Dietary Salt Intake in CKD Patients – Trial Summary and Commentary

Anastasiia Zykova, ISN Advancing Clinical Trials Network member, summarizes the design and outcomes of a study from the ISN-ACT Global Trials Focus' most recent global trials selection. Evaluation of a simple, low-cost intervention to empower people with chronic kidney disease to reduce their dietary salt intake: OxCKD1, a multi-center randomized controlled trial. Summary In this trial, 193 adult participants...

October 2, 2023News, ResearchRead more...

Explore the Reshaped ISN International Network of Chronic Kidney Disease Cohort Studies (iNET-CKD) Network Map

The newly updated ISN iNET-CKD Network cohorts map features a new layout, revised information on cohorts, and additional data. Access the ISN iNET-CKD Network cohorts map here. The ISN iNET-CKD Network is one-of-a-kind. It tracks ongoing chronic kidney disease (CKD) cohort studies located worldwide, facilitating an exchange of insights into CKD progression and its global implications. This network's...

September 18, 2023News, ResearchRead more...

Read the Latest ISN Journal Editorial Selections

Kidney International® Repurposing Drugs for Diseases Associated With Podocyte Dysfunction Due to recent advances in understanding the molecular and cellular mechanisms underlying podocyte injury, there is potential for repurposing already approved therapeutics for treating these disorders. This mini-review explores the complexities of repurposing drugs for kidney treatment, emphasizing the importance of extensive testing, emerging technologies, early intervention,...

September 18, 2023ELP, Journals, News, ResearchRead more...

Forewarned or Forearmed: Do Automated Medication-targeted Alerts Improve AKI Outcomes? Trial Summary and Commentary

Nikolay Bulanov, ISN-ACT Global Trials Focus Subgroup member, summarizes the design and outcomes of a study from the ISN-ACT Global Trials Focus' most recent global trials selection and comments on the trial's limitations. A randomized clinical trial assessing the effect of automated medication-targeted alerts on acute kidney injury outcomes Summary: In this parallel-group, pragmatic, open-label trial, 5060 hospitalized...

September 18, 2023News, ResearchRead more...

Latest ISN Journal Editorial Selections  

Kidney International® Managing the Symptom Burden Associated With Long-term Dialysis: Conclusions From a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference In 2022, patients, doctors, therapists, nurses, pharmacists, and researchers came together at the KDIGO Controversies Conference, “Symptom-Based Complications in Dialysis,” to examine and agree on essential ideas about recognizing and treating symptoms in dialysis patients....

September 4, 2023Journals, News, ResearchRead more...

Results From the iNET-CKD Study on Hemoglobin in Global CKD Populations Published in Kidney International Reports®

The "Regional Variation in Hemoglobin Distribution Among Individuals With CKD: the ISN International Network of CKD Cohorts" study, led by ISN iNET-CKD* investigators, addresses anemia's global prevalence in people living with chronic kidney disease (CKD). Read the manuscript here. Current guidelines suggest a uniform hemoglobin (Hb) range for all people with CKD, but this research examines...

September 4, 2023News, ResearchRead more...

High-dose Hemodiafiltration or Hemodialysis for Patients With Kidney Failure? Michele Provenzano on the CONVINCE Trial

Michele Provenzano summarizes the design and outcomes of the ISN-ACT Global Trials Focus’ latest “Trial of the Month” and comments on possible mechanisms of the benefit and limitations of the results. A CONVINCE-ing trial for Hemodiafiltration Effect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure Reviewed by Dr. Provenzano, ISN-ACT Global Trials Focus Subgroup...

September 4, 2023News, ResearchRead more...

How to Write a Winning Abstract in Ten Easy Stages

Watch the webinar “Winning Steps for a Successful WCN’24 Abstract Submission and Beyond.” It’s abstract submission season! How can you write a good abstract that will get accepted to WCN’24? WCN’24 abstract reviewers Sabine Karam, Magdalena Madero, Roberto Pecoits-Filho and Rob Walker have got you covered! Follow their foolproof advice on writing a winning abstract...

September 4, 2023Education, News, Research, WCNRead more...

Help Shape the Global Kidney Care Landscape: Download, Use and Share the ISN-Global Kidney Health Atlas Region-specific Summary Slides

The ISN-Global Kidney Health Atlas (ISN-GKHA) team has produced region-specific summary slides from the 2023 ISN-GKHA edition. Access the documents* here: Africa, Eastern and Central Europe, Latin America, Middle East, NIS and Russia, North America and the Caribbean, North and East Asia, Oceania and South East Asia, South Asia, Western Europe. Why are these slides useful? This...

August 22, 2023Featured, News, ResearchRead more...

Latest ISN Journal Summaries

Kidney International ® Editorial Selections The Power of “Negative” Experiments: Harry Goldblatt’s Pathway to Discovering How Renal Ischemia Causes Hypertension The author demonstrates that Harry Goldblatt’s willingness to conduct and publish studies with negative outcomes led to a fundamental understanding of blood pressure control within less than a decade of his initial discovery, published in...

August 22, 2023Journals, News, ResearchRead more...

Listen to the Discussion on ISN’s First Consensus Guidance for Pre-clinical Animal Studies in Translational Nephrology (TRANSFORM) with Fergus Caskey, Masaomi Nangaku and Agnes Fogo

Fergus Caskey, chair of the ISN Research Working Group, interviews ISN President Masaomi Nangaku and immediate Past President Agnes Fogo on the first guidance for the optimal conduct of translational animal studies for developing new drugs to treat kidney disease. Listen to the ISN Global Kidney Care Podcast here. Learn about: The initiative’s goal of improving translational...

July 17, 2023Featured, News, ResearchRead more...

Newly Revised Edition of the ISN-ACT Clinical Trials Toolkit Available Now!

The ISN-ACT Clinical Trials Toolkit, launched in 2020, is designed to guide anyone starting a clinical trial or participating as a trial site. This user-friendly online toolkit is for nephrologists and researchers in kidney care from all parts of the world – regardless of their level of clinical trial experience or local resources. The toolkit includes...

July 17, 2023Featured, News, ResearchRead more...

“Trying to Solve the Mystery of CKDu Together”: The ISN i3C “Work in Progress” Meetings Highlight Advances and Research Opportunities in CKDu

ISN i3C Network members and ISN staff at one of the recently held "Work in Progress" meetings The ISN i3C (CKDu) Network (International Consortium CKDu Collaborators) brought together more than 80 participants at two online interactive meetings held in June and July to discuss current, notable work on chronic kidney disease of unknown origin (CKDu). In...

July 17, 2023Featured, News, ResearchRead more...

Kidney International® Publishes ISN First Consensus Guidance for Pre-clinical Animal Studies in Translational Nephrology 

Kidney International® has published the "International Society of Nephrology First Consensus Guidance for Pre-clinical Animal Studies in Translational Nephrology." This open-access paper was developed from the "First Consensus Meeting on Guidance for Optimal Pre-Clinical Animal Studies in Translational Nephrology" (TRANSFORM) hosted by the ISN in Brussels, Belgium, in October 2022. This is the first such guidance. The recommendations...

July 3, 2023News, ResearchRead more...

“It’s an Extraordinary Global Effort”: Liz Lightstone Introduces the 2023 ISN-Global Kidney Health Atlas; Speakers David Johnson and Ikechi Okpechi  Comment on Findings – Watch the Webinar Recording Now!

Watch a recording of the ISN Webinar "ISN-GKHA (Atlas): Findings and Policy Implications for Europe and for the Americas" here. Moderator Liz Lightstone joined speakers David Johnson and Ikechi Okpechi to discuss the extent of gaps in provision and access to kidney care across Europe and the Americas. The recently published 2023 ISN-Global Kidney Health Atlas...

July 3, 2023News, ResearchRead more...

Discuss the SWIFT Trial Live With ISN and Key Experts During the Upcoming #NephTrials on July 18

Join Rachael Morton, principal investigator of the SWIFT trial, in conversation with ISN-ACT (clinical trials) Committee members Michael Walsh and Angela Yee Moon Wang* at 9 p.m. EDT (convert to your time zone here) on July 18.  They will be joined by #NephJC representatives Swapnil Hiremath and Joel Topf to discuss the protocol for...

July 3, 2023News, ResearchRead more...

Catch Up Now! Watch a Recording of the ISN Webinar on the First Consensus Guidance for Pre-clinical Animal Studies in Translational Nephrology (TRANSFORM)

The ISN webinar on the first guidance on the optimal conduct of translational animal studies for developing new drugs to treat kidney disease took place on May 30, 2023. Watch the recording here. Moderators Agnes Fogo and Fergus Caskey* discussed the guidance with ISN President Masaomi Nangaku and TRANSFORM meeting Steering Committee member Richard Kitching. The guidance...

June 19, 2023Initiatives, News, ResearchRead more...