Research

A Simple Method to Reduce Hypotension During Hemodialysis: Ascending-Descending Ultrafiltration With Linear Sodium Profiling

ISN-ACT Global Trials Focus editorial team member Dominik Tuechler summarizes the design and outcomes of one of the ISN-ACT Global Trials Focus's latest trial selections. The "Trial of the Month" is available in several languages, now including German. Read all global trial selections from the ISN-ACT initiative here. In addition, in the ISN 'Guide for Everyone' series, selected...

July 1, 2024News, ResearchRead more...

Explore the Latest ISN Global Trials Focus Selection, Featuring a “Trial of the Month” on the Phase 2 Trial of Cemdisiran in Adult Patients with IgA Nephropathy

ISN-ACT Global Trials Focus editorial team member Megan Borkum summarizes the design and outcomes of the latest ISN-ACT Global Trials Focus "Trial of the Month." The "Trial of the Month" is available in several languages, now including German. Read all global trial selections from the ISN-ACT initiative here. In addition, in the ISN 'Guide for Everyone' series, selected clinical trials...

June 18, 2024News, ResearchRead more...

New Section on Risk Matrix Available Now in the ISN-ACT Toolkit

The ISN-ACT Toolkit has been extended to include a chapter on risk management – a fundamental pillar in the planning and executing of clinical trials that helps categorize risks based on their likelihood of occurrence and potential impact on the study. This new section was contributed by ISN-Advancing Clinical Trials Committee member Dr. Paula Andrea...

June 18, 2024News, ResearchRead more...

Advancing #Green Nephrology: Strategies and Insights From ISN Emerging Leaders Cohorts Published in Scientific Journals 

The paper "Climate Change, Kidney Health, and Environmentally Sustainable Kidney Care" by ISN Emerging Leaders Program (ELP) cohort 2 members has been published in the Journal of the American Society of Nephrology (JASN).   Read the paper here  The cohort conducted a cross-sectional survey to:   Understand knowledge, attitudes, and practices among healthcare professionals concerning the link between climate...

June 3, 2024ELP, Grants, News, ResearchRead more...

Avacopan and Rituximab – A Promising Combination for Patients With ANCA-Associated Vasculitis

Read all global trial selections from the ISN-ACT initiative here. The “trial of the month” is available in several languages. In addition, selected clinical trials are demystified for the layperson. ISN-ACT Global Trials Focus Subgroup member Nikolay Bulanov summarizes the design and outcomes of one of the ISN-ACT Global Trials Focus’s latest trial selections. Efficacy and safety of...

June 3, 2024News, ResearchRead more...

Latest ISN Journal Editorial Selections 

Kidney International®  Time for Action: Recognizing Chronic Kidney Disease as a Major Noncommunicable Disease Driver of Premature Mortality  This editorial outlines the significant global burden of chronic kidney disease and highlights the timeliness of a global consensus statement from the ISN, the European Renal Association, the American Society of Nephrology, regional societies, and experts, recently published...

June 3, 2024News, Research, Young nephrologistsRead more...

American Journal of Kidney Diseases Publishes Paper From 2023 ISN-Global Kidney Health Atlas Data

The paper "Organization and Structures for Detection and Monitoring of CKD Across World Countries and Regions: Observational Data From a Global Survey" has been published in the American Journal of Kidney Diseases. Read the paper by Tungsanga et al. here The ISN-Global Kidney Health Atlas (ISN-GKHA) is a worldwide survey assessing current kidney care capacity. Early detection...

May 27, 2024News, ResearchRead more...

Sleep-HD Trial Results: The Quest Continues for an Effective Therapy For Insomnia in Hemodialysis Patients

Read all global trial selections from the ISN-ACT initiative here. The “trial of the month” is available in several languages. In addition, selected clinical trials are demystified for the layperson. ISN-ACT Global Trials Focus editorial team member Megan Borkum summarizes the design and outcomes of one of the ISN-ACT Global Trials Focus’s latest trial selections. Effectiveness...

May 21, 2024News, ResearchRead more...

Latest ISN Journal Editorial Selections

Kidney International® Home Dialysis:  Conclusions From a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference In May 2021, KDIGO held a conference on expanding home dialysis emphasizing the need for policy alignment, resources, and shared decision-making between patients, care partners, and healthcare teams to improve access and use. The conference stressed the need to advocate for...

May 21, 2024Journals, News, ResearchRead more...

Discover the Newly Reviewed ISN-ACT Clinical Trials Toolkit With New Content!

The ISN-ACT Clinical Trials Toolkit is designed to guide anyone starting a clinical trial or participating as a trial site. It is aimed at nephrologists and researchers in kidney care worldwide, regardless of their level of clinical trial experience or local resources. The toolkit includes contributions from over 25 ISN-ACT Toolkit subgroup members – –...

May 6, 2024News, ResearchRead more...

Latest ISN Journal Editorial Selections

Kidney International® Improving and Maintaining Quality of Hemodialysis in Areas Conflicted by War: A Call to Action! Alasfar and colleagues discuss the severe impact of the Syrian war on kidney replacement therapy in the region, highlighting logistical challenges and compromised standards of care. They suggest key strategies to help manage kidney care in conflict areas, including understanding...

May 6, 2024Journals, News, ResearchRead more...

Clinical Trial on Different Fluids for Kidney Transplantation Summarized for the Layperson

A new trial has been added to the  “ISN Global Kidney Trials Insights: A Guide for Everyone.” Read the guide on balanced crystalloid solution versus saline in deceased donor kidney transplantation. The guide is based on the ISN-ACT Global Trials Focus (GTF) summaries. It aims to demystify clinical trials for the layperson, providing clear and accessible explanations of...

May 6, 2024News, ResearchRead more...

Explore the ISN Global Trials Focus Selection for February and March, Featuring a “Trial of the Month” on the Efficacy and Safety of Aldosterone Synthase Inhibition 

ISN-ACT Global Trials Focus editorial team member Neeru Agarwal summarizes the design and outcomes of the latest ISN-ACT Global Trials Focus "Trial of the Month."  The "Trial of the Month" is available in several languages, now including German. Read all global trial selections from the ISN-ACT initiative here. In addition, selected clinical trials are demystified for the layperson.  Part of the...

April 23, 2024News, ResearchRead more...

Explore Global Variance in Kidney Care Capacity: Papers Summarizing ISN-GKHA Regional Data Published in Kidney International® Supplements

The 2023 ISN Global Kidney Health Atlas (GKHA) sheds light on the current global capacity to deliver kidney care. Read the Kidney International® Supplements papers here A collection of papers published in Kidney International® Supplements focuses on each of the ten ISN regions, presenting a comprehensive overview of kidney care services by world region. They highlight...

April 8, 2024News, ResearchRead more...

Sharing Expertise to Establish Renal Registries Worldwide: Read the ISN SharE-RR Publication Introducing Its Toolkit

The ISN Sharing Expertise to Support the Set-up of Renal Registries (ISN SharE-RR) initiative develops resources to help establish or develop renal registries in emerging countries. Find more information on SharE-RR here The SharE-RR Advisory Group has created a step-by-step toolkit to guide nephrologists, public health officials, and others to establish and maintain successful, sustainable renal...

April 2, 2024News, ResearchRead more...

Protecting IgA Nephropathy Patients: Sparsentan Reduces Proteinuria and Preserves Kidney Function Through to Two Years

ISN-ACT Global Trials Focus editorial team member Neeru Agarwal summarizes the design and outcomes of one of the ISN-ACT Global Trials Focus's latest trial selections. Read all global trial selections from the ISN-ACT initiative here. The "trial of the month" is available in several languages. In addition, selected clinical trials are demystified for the layperson. Efficacy and safety...

March 18, 2024News, ResearchRead more...

A Ray of Light for People Living With Chronic Kidney Disease: A Promising Digital Physical Activity Intervention

ISN-ACT Global Trials Focus editorial team member Megan Borkum summarizes the design and outcomes of one of the ISN-ACT Global Trials Focus's latest trial selections. Read all global trial selections from the ISN-ACT initiative here. The "trial of the month" is available in several languages. In addition, selected clinical trials are demystified for the layperson. Evaluating the effect...

March 4, 2024News, ResearchRead more...

Sparsentan Decreased Proteinuria, but Failed to Slow eGFR Decline in FSGS: Data From the DUPLEX Trial – New Selection of Global Trials Out Now!

ISN-ACT Global Trials Focus Subgroup member Anastasiia Zykova summarizes the design and outcomes of the team's latest "Trial of the Month." Stay updated on the latest research and developments in kidney care: Access the new selection of global trials from the ISN-ACT initiative here. The "Trial of the Month" is available in several languages. Sparsentan Versus Irbesartan...

February 19, 2024News, ResearchRead more...

The Lancet Global Health Publishes ISN Paper on Global Insights From the 2023 ISN-Global Kidney Health Atlas

The paper "An Update on the Global Disparities in Kidney Disease Burden and Care Across World Countries and Regions" has been published in The Lancet Global Health. Read the paper here. In the same edition, The Lancet Global Health published an editorial on the paper: "The Major Global Burden of Chronic Kidney Disease." Read the editorial...

February 19, 2024Initiatives, News, ResearchRead more...