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ISN Journal summaries on IgA nephropathy and conservative kidney management

Kidney International® 

Treatment of patients with IgA nephropathy: a call for a new paradigm 

Current treatments for IgA nephropathy (IgAN), including supportive care and corticosteroids, have limited success and significant side effects.  

Advances in understanding IgAN’s pathogenesis have led to new targeted therapies and a proposed dual approach: targeting IgAN-specific mechanisms (e.g., pathogenic IgA production) and managing kidney disease progression with protective therapies like RAS and SGLT2 inhibitors.  

Future treatment strategies will likely focus on integrating multiple therapies to maximize nephron preservation. 

 

Kidney International Reports® 

Conservative kidney management in the Middle East and North Africa: attitudes, practices, and implementation barriers 

This study examined nephrologists’ perspectives on conservative kidney management (CKM) in the Middle East and North Africa region.  

Results from the online survey showed that despite high awareness, only 20% of participants consistently offered CKM, and just 16% had a formal CKM program at their institution. The main barriers were financial constraints, resource shortages, and cultural factors. 

Regional research is needed to address these challenges and improve CKM implementation. 

Access the CKM Curriculum at the ISN Academy 

 

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