Deciphering the Mechanisms Responsible for PKD: Announcing the Winner of the ISN 2025 Lillian Jean Kaplan Prize
Please join us in congratulating Professor Marie Trudel, the ISN 2025 Award winner for the Lillian Jean Kaplan International Prize.
Professor Trudel will receive the prize during the ‘Bridging the Gap: PKD Research and Clinical Care Perspective – Kaplan PKD Session’ at the ISN World Congress of Nephrology 2025 in New Delhi, India. She will deliver a scientific talk and participate in a roundtable with other polycystic kidney disease (PKD) experts at this session on February 7, from 2:15 to 3:45 p.m.
Professor Marie Trudel (Canada)
The Lillian Jean Kaplan International Prize recognizes individuals for excellence and leadership in PKD clinical or basic research whose seminal scientific work has advanced PKD knowledge and treatment.
Professor Trudel, from the Department of Medicine at the Université de Montréal, Quebec, Canada, was awarded the prize for the comprehensive research program she established on autosomal dominant polycystic kidney disease (ADPKD).
The Trudel laboratory is working on deciphering the cellular and physiologic mechanisms responsible for PKD by developing the most relevant mouse models that closely reproduce human renal and extrarenal ADPKD manifestations. Studies from her team have advanced the understanding of the molecular pathogenesis of ADPKD and identified potential therapeutic targets for PKD treatment toward preclinical and clinical investigation.
Professor Trudel joined the Institut de Recherches Cliniques de Montréal (IRCM) as the unit director of Molecular Genetic and Development in 1989 and is a professor in the Department of Medicine and Biochemistry at Université de Montréal and adjunct professor at McGill University in Quebec, Canada. She obtained her Ph.D. in 1982 from Université Pierre et Marie Curie in Biochemistry with Dr. Marianne Grunberg-Manago (president, National Academy of Science) at Institut de Biologie Physico-Chimique, Paris. She did post-doctoral training with Drs. Mark Meuth and Tomas Lindahl (Nobel laureate 2015), at Imperial Cancer Research Fund, London, UK, and with Dr. Frank Costantini at Columbia University, NY, USA.
Professor Trudel received studentships and fellowships from Foreign Affairs France, the Medical Research Foundation, Paris, the Institut de Recherche en Santé et Sécurité du travail Quebec, the American Leukemia Society, the Centennial Fellowship Medical Research Council of Canada, and scholarships from Fonds de Recherche du Québec – Santé.
