Insight

October 04, 2021

 FEATURES
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You Are Invited: Connect with the Global Kidney Community - Register for WCN’22

Registration for the 2022 World Congress of Nephrology (WCN'22) is now open.
Be part of a global gathering to exchange the latest in kidney science and clinical applications.
The congress will connect kidney health professionals through a robust virtual program to advance equitable kidney care worldwide.
In-person activities in Kuala Lumpur will be announced if considered safe and feasible.
Visit the WCN'22 webpages for the latest updates on your access to the congress.
Take advantage of the Early Bird deadline when you register before midnight CET, November 24, 2021.
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Kidney International Publishes the KDIGO 2021 Guideline for Glomerular Disease Management

The guideline was developed to assist clinicians caring for patients with glomerulonephritis while being mindful of implications for policy and cost.
Read the "KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases" here.
Kidney International also presents an executive summary of the guideline in their October issue.
The guideline provides practical, evidence-based recommendations and useful infographics based on input from relevant experts to guide diagnosis, prognosis, treatment, and special situations. It also offers research recommendations for areas where there are gaps in knowledge.
 ISN LATEST NEWS
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Membership

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ISN Membership: Now with More Equitable Access for All

As of September 2021, a new ISN Membership fee structure went into effect offering more accessible fees for ISN members based on their country’s economic context. Certain individuals can now receive up to 70% reduction on Full ISN Membership - check our website for more information.
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Dr. Karen Courville, SPNH president (far left), alongside Dr. Norman Bustamante, SPNH secretary, and staff members at the Dr. Gustavo N. Collado Hospital of the Caja de Seguro Social (CSS) in Chitré, Herrera, on World Kidney Day 2018

Celebrating ISN Collective-Member Societies:
The Panamanian Society of Nephrology and Hypertension

The ISN’s series on Collective-Member Societies shifts its focus to the
Latin America Region and spotlights the Panamanian Society of Nephrology and Hypertension (SPNH).
We spoke to SPNH President Karen Courville about ongoing local initiatives to raise kidney health awareness in the region.
The SPNH is currently developing strong campaigns to raise awareness of two important pathologies that cause chronic kidney disease: hypertension and diabetes. A series of bi-weekly webinars will be broadcast from October onwards, focusing on the importance of addressing hypertension in various contexts, including in diabetic, CKD, and transplant patients.
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research

Grants

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UCLA doctors at Hospital Roosevelt, Guatemala, who helped perform kidney transplants there in 2017

Ten Days Left to Apply to the ISN-TTS Sister Transplant Centers Program

Apply to the Sister Transplant Centers (STC) Program here.
The deadline is October 15, 2021.
The Sister Transplant Centers (STC) Program, a joint initiative of the ISN and The Transplantation Society (TTS), fosters global partnerships between health centers to improve treatment and outcomes for kidney transplant patients in low-resource settings.
A sister center partnership set up in 2013 between the University of California, Los Angeles (UCLA) and Fundanier helped implement a deceased donor program and comprehensive pediatric nephrology care for children in Guatemala. Read more on the success of this collaboration here.
Please contact STC@theisn.org if you have any questions. We look forward to receiving your applications.
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Apply to Join the Second Cohort of the Emerging Leaders Program Before October 15

Are you an early-career professional interested in developing leadership skills to shape and advance the future direction of global kidney health?
Iqbal Abdul Hafidz, from Malaysia, was one of ten successful candidates in the first ELP cohort. He comments, “This has been a truly amazing experience - meeting new friends from across the globe and learning how they practice in diverse backgrounds. The ELP showed me how everyone has a role to play in improving the standard of kidney care, not only in their own country but also worldwide.”
Open to all ISN members, renal pathologists are especially encouraged to apply to the program. The deadline to apply is October 15, 2021.
Find out more here.
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Ahmad Naseer Kaihan

Introducing the Second Detlef Schlöndorff ISN Fellow

Ahmad Naseer Kaihan has become the second Detlef Schlöndorff ISN Fellowship recipient. His training is supported by the Detlef Schlöndorff Fellowship Fund.
Ahmad Naseer Kaihan will travel from his home center, the Payem Sehat Hospital in Afghanistan, to the MGM Healthcare center in India. He will spend 12 months training in clinical nephrology under supervision from Georgi Abraham and then return to his home region to help improve kidney care using skills gained during his fellowship.
Read more about Detlef Schlöndorff and the Detlef Schlöndorff ISN Fellowship here.
Donate to the Detlef Schlöndorff Fellowship Fund here or send a US check to the International Society of Nephrology, 340 North Ave, 3rd Floor, Cranford, NJ 07016, USA, with the reference “Detlef Schlöndorff Fellowship Fund.”
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Research

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Join us Tomorrow for the Second Webinar on MRAs and DKD Management

The webinar, "Amplification of the presentation of the main results of the FIGARO trial," will take place at 3 p.m. on October 5.
Gerasimos Filippatos, Greece, Javed Butler, USA, and Adeera Levin, Canada, will examine the results of the FIGARO-DKD study and assess its implications for clinical practice in nephrology and cardiology:
  • Trial design and main results of efficacy and safety
  • A conversation between a cardiologist and a nephrologist
A Q&A session will follow these talks.
For content details and a registration link in Japanese, click here.
セッション内容の詳細や日本語でのお申し込みはこちら。
The session will be moderated by Masaomi Nangaku, Japan and David Wheeler (ISN - ACT Chair), UK.
This webinar is supported by an unrestricted educational grant from
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Chapter Three of the Narrative Based Clinical Trials
(ISN-ACT) Toolkit to Be Unveiled in the Next Edition of Insight

Narrative storytelling is a great way to explain complex topics to make them more accessible. Using a fictional clinical discussion, the third chapter of the Narrative Based Clinical Trials (ISN-ACT) Toolkit will outline what it takes to become a trial site: A group of nephrologists aiming to become a trial site share their experiences as they confront various issues and overcome the challenges involved.
Three chapters of the Narrative Based Clinical Trials (ISN-ACT) Toolkit are scheduled for release per year
(February-June-October). Check out the first two chapters on trial randomization and trial design here.
Don’t miss chapter three on October 18!
The ISN would like to thank the ISN-ACT Clinical Trials Toolkit subgroup members for their hard work and dedication in developing this series of stories.
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Events

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Prepare Your Abstract Submission and Travel Grant Application for the ISN Frontiers Meeting in Bergamo, Italy, from June 23-25, 2022

The ISN will shortly accept abstracts to the ISN Frontiers Meeting, ‘Complement-related kidney diseases: classification, genetics, and treatment’ on these topics.
Accepted abstracts will be presented as posters at the meeting and published in Kidney International Reports. A selection of authors will
present their abstracts orally.
The deadline is February 16, 2022.
The Frontiers meeting in Bergamo is planned as an in-person event. With this in mind, the ISN will soon start accepting travel grant applications for the meeting; the application period will be open until February 16, 2022. Find more details here.
The ISN and the Mario Negri Institute for Pharmacological Research continue to monitor COVID-19-related developments and follow advice from national and international authorities to ensure a safe environment for delegates.
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Vote in the “Community Choice Film Selection" Event

The 2022 Community Choice Film Selection presents entries to the 2021
ISN Community Film Event that narrowly missed the shortlist, offering them a further opportunity to be shortlisted for the Best Film Award 2022.
Online voting will close on December 6, 2021.
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Share a Story from Your Community:
Submit a Film to the ISN Community Film Event

Raise awareness of issues affecting kidney patients and those who care for them by sharing their stories with a global audience at the ISN Community Film Event.
Shortlisted films will be screened during the ISN Community Film Event, taking place during WCN’22. The audience will vote for the Best Film Award 2022.
The deadline is December 8, 2021.
Follow #ISNFilmEvent to stay up to date on the event.
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Save the Dates for the ISN Frontiers Meeting on Infections and the Kidney

The meeting will take place from September 22 to 25, 2022, in New Delhi, India. Look out for more details coming soon to the Frontiers website and subscribe to the Frontiers newsletter here to stay informed.
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ISN Participates

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ISN in Action: Join us for the ISN-SIN Joint Session at
the 62nd Annual Meeting of the Italian Society of Nephrology

The 62nd Annual Meeting of the Italian Society of Nephrology (SIN) will be held in hybrid format from October 6-9, 2021, in Rimini, Italy.
Consult the event program here.
Listen to Agnes Fogo, ISN president, on the topic "ISN in Action" on October 9. She will focus on activities within the Sister Renal Centers and Mentorship granting programs.
This presentation is part of the ISN-SIN joint session from 7:30-8:30 a.m. (CEST), which will also feature talks under the theme “ISN and SIN in Action During the COVID Pandemic” from Piergiorgio Messa, SIN president, and Carmine Zoccali.
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Awards

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Maolynne Miller

Join Us for the Presentation of the ISN Pioneer Award for North America and the Caribbean

The 4th Jamaican Paediatric Nephrology Conference 2021, hosted by the Jamaica Kidney Kids Foundation with support from the International Pediatric Nephrology Association, will take place virtually on October 24, 2021, in Jamaica.
Register for the conference here.
The conference will include the presentation of the ISN 2021 Pioneer Award for North America and the Caribbean to Maolynne Miller from Jamaica at 10:25 a.m. EST. ISN President Agnes Fogo will introduce the award ceremony, and Rulan Parekh, ISN Regional Board chair, will highlight Maolynne's achievements.
Find out more about Maolynne Miller and her work here.
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YOUNG NEPHROLOGISTS

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Alexia Romero placing a tunneled catheter for hemodialysis during one of her shifts at the Hospital Civil of Guadalajara

A Day in the Life of a Resident on a Nephrology Ward in Mexico

My name is Alexia Romero, and I am a nephrology resident at the Hospital Civil of Guadalajara, a 1,200-bed tertiary care center in Mexico.
At the start of a new day in the nephrology ward, alongside two resident fellows and two undergraduate interns, I know it's going to be a busy day.
I am responsible for approximately sixty patients with chronic kidney disease. My first activity of the day is to assess each patient on the ward. We review laboratory and imaging tests and discuss and modify treatment accordingly, focusing on vital signs, urine output, and fluid balance.
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EDUCATION

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Circulate an International Survey to Help Develop Physical Activity Guidelines for PD Patients

An international survey has been developed to help design exercise guidelines for peritoneal dialysis (PD) patients.
Access the survey in English, Portuguese, Spanish, or Thai.
The survey on exercise and physical activity practices and perceptions among PD clinicians is supported by the International Society for Peritoneal Dialysis and approved by the University of South Australia Human Research Ethics Committee.
The survey comprises 13 questions and takes approximately 8 minutes to complete.
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Register for the ISN Webinar on Conclusions from the International Home Dialysis Roundtable

Join us on October 28, 2021, at 2.30 p.m. CEST to explore findings on home dialysis from the International Home Dialysis Roundtable
(Roundtable supported by Baxter).
Mallika Mendu, Simon Davies, Daniel Gallego, and Vivekananad Jha will examine:
  • Best practices
  • Successful strategies
  • Overcoming challenges
Read the paper "Expanding Utilization of Home Dialysis: An Action Agenda from the First International Home Dialysis Roundtable."
This webinar is sponsored by industry. An application has been made to the UEMS EACCME® for CME accreditation of this event.

Upcoming Webinars

Tuesday, October 5, 3 p.m. CEST

ISN Webinar Series: MRAs and DKD Management
Amplification of the Presentation of the Main Results of the FIGARO Trial

Speakers: Gerasimos Filippatos, Greece
Javed Butler, USA
Adeera Levin, Canada
Moderators: Masaomi Nangaku, Japan
David Wheeler, UK
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This webinar is supported by an unrestricted educational grant from
Friday, October 8, 4 p.m. CEST

ISN-KDIGO Webinar:
Glomerular Diseases Guideline - Part 2

Speakers: Juan M. Mejia-Vilet, Mexico
Keisha L. Gibson, USA
Moderator : Brad Rovin, USA
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Thursday, October 28, 2:30 p.m. CEST

ISN Webinar:
Expanding Utilization of Home Dialysis - Findings of the International Home Dialysis Roundtable

Speakers: Mallika Mendu, USA
Simon Davies, UK
Daniel Gallego, Spain
Moderator : Vivekananad Jha, India
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Recorded Webinars

Nuances in Nephrology:
Coronary Artery Revascularization Strategy in the Advanced Stage of CKD

ISN Frontiers Webinar:
New Insights into Clinical Management of
Complement-mediated Thrombotic Microangiopathies

ISN Webinar Series on MRAs and DKD Management
MRAs in CKD: Lessons from a Scientist, an Investigator,
and a Trialist

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Advocacy

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Discover the Latest Edition of the DICG Newsletter

Read the September issue of the Declaration of Istanbul on Organ Trafficking and Transplant Tourism (DICG) newsletter here.
The current issue focuses on:
  • A feature on organ trafficking in Assam, written by DICG members in India published in the national press.
The DICG is a joint initiative of the ISN and the Transplantation Society.
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ISN Journals

eDigest

Meet Three Newly-Appointed ISN-KI Editorial Fellows and Seven ISN-KI Editorial Interns

Please join us in welcoming the 2021 ISN-KI Editorial Fellows who will train alongside the Kidney International (KI) editorial team from October 2021 to April 2023.

In addition, the ISN and KI are delighted to announce the first seven ISN-KI Editorial Internships. These interns, early career researchers from ISN regions around the globe, will receive personal mentorship from a member of the KI editorial team to develop their editorial skills.
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COVID-19

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Kidney International (KI) on COVID-19

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Kidney International Editorial Selections

KI-Editorial

The Emerging Field of Non-human Leukocyte Antigen Antibodies in Transplant Medicine and Beyond

This review provides a comprehensive summary of the paradigm-changing concept of immunity to the non-HLA angiotensin II type 1 receptor (AT1R) that began from careful bedside clinical observations and was validated with the detection of anti-AT1R antibodies, leading to clinical intervention.
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Development of an International Delphi Survey to Establish Core Outcome Domains for Trials in Adults with Glomerular Disease

Outcomes relevant to treatment decision-making are inconsistently reported in trials involving glomerular disease. This clinical trial aimed to establish a
consensus-derived set of critically important outcomes designed to be described in all future trials through an online, international two-round Delphi survey in English.
The authors demonstrate how consistent reporting of outcomes in trials involving glomerular disease can help improve patient-centered decision-making.
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Kidney International Reports Editorial Selection

KIR-Editorial

Immortal Time-Bias-Corrected Survival of Highly-sensitized Patients and HLA-Desensitized Kidney Transplant Recipients

Nephrologists from the University Hospital Grenoble, France, assessed the efficacy of desensitization and compared the survival of desensitized patients with similarly sensitized or sensitized patients still on a waiting list.
They found that HLA-desensitization was effective for highly sensitized patients and gave access to kidney transplantation without detrimental effects on patient or graft survival rates.
An accompanying commentary, “What is Best Alternative for Highly Sensitized Patients Awaiting Kidney Transplantation?” discusses the relevance of these findings when considering the quality of life and cost of transplantation.